How Much Does Sermorelin Cost? | A-Z Guide

Researchers interested in sermorelin’s uses and benefits may be curious about how much sermorelin costs. 

Many aspects of sermorelin’s use, benefits, and side effects are still under-researched, and this presents researchers with numerous avenues for further study including:

• Sermorelin for muscle growth and anti-aging purposes
• Long-term cardiovascular benefits
• Compliance with other therapies used to treat Growth Hormone Deficiency (GHD)

We put this guide together to help researchers gain a better understanding of the costs involved in researching this promising peptide.

Below, researchers will find an overview of what sermorelin is, some common dosages, and most notably, how much it costs, and the best place to source peptides online.

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What is Sermorelin?

Sermorelin is a peptide analogue of growth hormone-releasing hormone (GHRH). It comprises the first 29 amino acids of endogenous human GHRH, making it the shortest synthetic peptide to have the full biological activity and functionality of GHRH [1].

Sermorelin’s main use is to assess growth hormone (GH) secretion and diagnose growth hormone deficiency (GHD). It works by producing a rapid hormone response and is much more efficient than other provocative tests [1].

Sermorelin is also used to treat children and adults with GHD. Available under the brand names “Geref” and “Gerel,” sermorelin is a widely used growth hormone secretagogue (GHS) that stimulates the pituitary gland to produce and secrete more HGH in patients with GHD [1].

As sermorelin is essentially a fully functional fragment of GHRH, it provides similar benefits to other forms of human growth hormone (HGH) therapy.
Approval for sermorelin as a drug has been discontinued in the U.S. since 2008; however, it’s still available to researchers as a reference material in most parts of the world.

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Benefits of Sermorelin

Having reviewed the available literature and data from clinical studies, our team has compiled a brief list of the main sermorelin benefits that researchers should be aware of. Researchers should bear in mind that the positive effects of sermorelin are indirect, as sermorelin is a peptide that releases more of the body’s natural GH, and it is the GH that has the benefits.

Sermorelin’s main benefits include:

Assessment of growth hormone (GH) secretion

Sermorelin is extremely effective at assessing growth hormone (GH) secretion in children and adults. It is used as a diagnostic tool to assess patients who exhibit signs of GHD syndrome. Sermorelin is currently the most effective test for diagnosing GHD [1].

Treatment of children and adults with GHD

Sermorelin is an effective treatment for children and adults with GHD. It has the full biological activity of human GHRH and is effective at stimulating the release of more endogenous GHRH [1].

Treatment of male hypogonadism

Studies have indicated that sermorelin may be beneficial for the treatment of some of the symptoms of male hypogonadism. Data indicates that it can be used to improve the body composition of men with metabolic syndrome or subclinical hypogonadism (SH) [2].

Purported benefits in healthy individuals

Although data regarding sermorelin’s use is limited to the diagnosis and treatment of GHD and SH, its role as a GHS and GHRH analogue means that it offers broadly similar benefits to other forms of GH supplementation.

Studies involving the administration of GH to healthy individuals suggests that GHRH analogues such as sermorelin can:

• Increase lean muscle mass [3]
• Reduce fat [3]
• Prevent age-related thinning of the skin [3]
• Improve body composition and increase sprint capacity [4]

As data on sermorelin’s clinical efficacy for these purposes is still lacking, this opens opportunities for future investigation by researchers, specifically for its application as a body composition or anti-aging agent, or as an enhancer of athletic performance overall.

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Sermorelin Side Effects

Sermorelin is considered safe when administered prudently, with most test subjects reporting minimal to no side effects. The most commonly reported minor side effects are [5]:

• Inflammation, redness, pain, or discomfort at the injection site
• Nausea
• Vomiting
• Headache
• Redness of the face
• Paleness
• Unusual taste in the mouth

Although less frequently reported, some test subjects report experiencing some more severe side effects. These include [6]:

• Inflammation in the mouth, tongue, lips, or other facial features
• Rash
• Hives
• Itching
• Difficulty breathing
• Tightness in chest

Any test subjects experiencing any of these side effects should cease their involvement in sermorelin research and consult with a medical professional immediately.

Clinical data about sermorelin’s long-term side effects is currently lacking. However, an analysis of safety data from growth hormone manufacturers' registries from 1988 through 2016 revealed no evidence that GH increases the risk of mortality, type-2 diabetes, new malignancy, or leukemia in patients without pre-existing risk factors [7].

A separate study into the impact of the GH on the kidney concluded that GH’s effect “has not yet been clarified” [8].

In the following section, we will tackle the question at hand; how much does sermorelin cost?

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How Much Does Sermorelin Cost?

Given the important gaps in our understanding of sermorelin, especially as regards its efficacy in treating symptoms of male hypogonadism [2] and its long-term safety, researchers may be curious about the cost of this research peptide.

Overall, the cost of sermorelin is in line with other types of GHS and GHRH analogues, depending on the vendor and the dosage sought.

Our preferred vendor, Xcel Peptides, currently sells sermorelin as a reference material at the following prices:

• Sermorelin 5mg – $40 USD

Research peptides are offered at a 10 percent discount to researchers who sign up for the Xcel Peptides email list.. Orders over $200 ship free within the U.S.

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Sermorelin Cost Per Dose

When designing a sermorelin administration protocol, the sermorelin doses chosen will be the primary factor in determining the cost. For research involving larger doses, the larger 5 mg sermorelin vials will prove to be more cost-effective:

• Research subjects taking larger doses of 200 mcg may be better served with a larger 5mg vial. One 5mg sermorelin vial costing $40.00 will provide 25 daily doses, giving a cost of $1.60 per day.

Assuming that researchers place an order after signing up for the email list and qualify for a 10 percent discount, the cost of administering the above doses would be $1.44 per.

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Do Researchers Need a Prescription to Buy Sermorelin Online?

Researchers do not need to have a prescription to buy sermorelin online, since it’s available as a reference material for research purposes. However, it’s worth noting that regulations applicable to compounds like sermorelin vary by country and jurisdiction.

In most countries, sermorelin acetate can be purchased online by researchers without any requirement to show a prescription.

Buying sermorelin online is perfectly legal, providing researchers use it in accordance with the terms and conditions provided by a reputable vendor.

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Where to Buy Sermorelin Online? | 2024 Edition

So where can researchers buy sermorelin online? There are a variety of online vendors currently offering sermorelin for sale. However, it’s important for researchers to thoroughly vet vendors before placing an order.

Buyers are advised to consult customer reviews and review the peptide quality, payment methods, and levels of customer service offered by vendors. Our team has tested the products of several different online sources and our preferred vendor is:

Xcel Peptides

Xcel Peptides is a premier vendor of sermorelin and other research peptides.

Here’s why we love them:

• Lab-Tested Sermorelin: Xcel Peptides sends their products to a third-party laboratory for HPLC-MS testing to ensure a minimum of 99% purity. The test results are easily accessible on their website for researchers to verify.
• Secure Payments: Xcel Peptides offers secure payment options, accepting all major credit cards as well as payments via Zelle, CashApp, and Venmo.
• In-Depth Resources: The company's website is filled with comprehensive research summaries for each peptide, including sermorelin.

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Bacteriostatic Water for Sermorelin

If researchers are ready to dive into Sermorelin study, don’t forget the supplementary materials required for proper preparation, storage, and handling.

The full set of requisite items includes bacteriostatic water, alcohol swabs, and more.

If gathering all these items sounds like a headache, that's perfectly normal. Stocking up on supplies is an annoyance and potential setback for many researchers. However, it is needed to properly conduct research.

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Sermorelin Costs | Verdict

For researchers curious about the cost of sermorelin, hopefully, this comprehensive guide has explained how to buy this research peptide at the most economical prices.

Researchers are already hard at work to see whether sermorelin indeed offers benefits like increased muscle mass, decreased fat, and enhanced athletic performance. In the absence of data from long-term clinical trials, sermorelin offers researchers a multitude of opportunities for further research, including the treatment of symptoms related to male hypogonadism and the cardiovascular and health benefits from extended periods of use.

Our preferred vendor carries high-quality sermorelin and other research peptides at the best possible prices.

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